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Construction of Comprehensive Dosage-Matching Core Histone Mutant Libraries for Saccharomyces cerevisiae.
Jiang S, Liu Y, Wang A, Qin Y, Luo M, Wu Q, Boeke JD, Dai J. Jiang S, et al. Genetics. 2017 Dec;207(4):1263-1273. doi: 10.1534/genetics.117.300450. Epub 2017 Oct 30. Genetics. 2017. PMID: 29084817 Free PMC article.
Saccharomyces cerevisiae contains two genes for each core histone, which are presented as pairs under the control of a divergent promoter, i.e., HHT1-HHF1, HHT2-HHF2, HTA1-HTB1 and HTA2-HTB2HHT1-HHF1, and HHT2-HHF2 encode histone H3 and H4 with identical amino acid sequenc …
Saccharomyces cerevisiae contains two genes for each core histone, which are presented as pairs under the control of a divergent promoter, i …
Yeast ASF1 protein is required for cell cycle regulation of histone gene transcription.
Sutton A, Bucaria J, Osley MA, Sternglanz R. Sutton A, et al. Genetics. 2001 Jun;158(2):587-96. doi: 10.1093/genetics/158.2.587. Genetics. 2001. PMID: 11404324 Free PMC article.
Transcription of the four yeast histone gene pairs (HTA1-HTB1, HTA2-HTB2, HHT1-HHF1, and HHT2-HHF2) is repressed during G1, G2, and M. For all except HTA2-HTB2, this repression requires several trans-acting factors, including the products of the HIR ge …
Transcription of the four yeast histone gene pairs (HTA1-HTB1, HTA2-HTB2, HHT1-HHF1, and HHT2-HHF2) is repressed during G1, G2 …
Amplification of histone genes by circular chromosome formation in Saccharomyces cerevisiae.
Libuda DE, Winston F. Libuda DE, et al. Nature. 2006 Oct 26;443(7114):1003-7. doi: 10.1038/nature05205. Nature. 2006. PMID: 17066037 Free PMC article.
In Saccharomyces cerevisiae, the histones H2A and H2B are encoded by two gene pairs, named HTA1-HTB1 and HTA2-HTB2 (ref. 8). Previous studies have demonstrated that when HTA2-HTB2 is deleted, HTA1-HTB1 dosage compensates at the transcriptional level(4, …
In Saccharomyces cerevisiae, the histones H2A and H2B are encoded by two gene pairs, named HTA1-HTB1 and HTA2-HTB2 (ref. 8). P …
Spt10 and Swi4 control the timing of histone H2A/H2B gene activation in budding yeast.
Eriksson PR, Ganguli D, Clark DJ. Eriksson PR, et al. Mol Cell Biol. 2011 Feb;31(3):557-72. doi: 10.1128/MCB.00909-10. Epub 2010 Nov 29. Mol Cell Biol. 2011. PMID: 21115727 Free PMC article.
In budding yeast, histones H2A and H2B are expressed from divergent promoters at the HTA1-HTB1 and HTA2-HTB2 loci. Here, we show that the major activator of HTA1-HTB1 is Spt10, a sequence-specific DNA binding protein with a putative histone acetyltransferase (HAT) d …
In budding yeast, histones H2A and H2B are expressed from divergent promoters at the HTA1-HTB1 and HTA2-HTB2 loci. Here, we sh …
SPT10 and SPT21 are required for transcription of particular histone genes in Saccharomyces cerevisiae.
Dollard C, Ricupero-Hovasse SL, Natsoulis G, Boeke JD, Winston F. Dollard C, et al. Mol Cell Biol. 1994 Aug;14(8):5223-8. doi: 10.1128/mcb.14.8.5223-5228.1994. Mol Cell Biol. 1994. PMID: 8035801 Free PMC article.
The Saccharomyces cerevisiae genome contains four loci that encode histone proteins. Two of these loci, HTA1-HTB1 and HTA2-HTB2, each encode histones H2A and H2B. The other two loci, HHT1-HHF1 and HHT2-HHF2, each encode histones H3 and H4. ...These experiments have …
The Saccharomyces cerevisiae genome contains four loci that encode histone proteins. Two of these loci, HTA1-HTB1 and HTA2-HTB2 …
Alterations in DNA replication and histone levels promote histone gene amplification in Saccharomyces cerevisiae.
Libuda DE, Winston F. Libuda DE, et al. Genetics. 2010 Apr;184(4):985-97. doi: 10.1534/genetics.109.113662. Epub 2010 Feb 5. Genetics. 2010. PMID: 20139344 Free PMC article.
Our previous studies in Saccharomyces cerevisiae identified the amplification of a histone H2A-H2B gene pair, HTA2-HTB2, in response to the deletion of the other H2A-H2B gene pair, HTA1-HTB1. ...Consistent with our mutant screen, we found that the introduction of DN …
Our previous studies in Saccharomyces cerevisiae identified the amplification of a histone H2A-H2B gene pair, HTA2-HTB2, in re …
Spt10 and Spt21 are required for transcriptional silencing in Saccharomyces cerevisiae.
Chang JS, Winston F. Chang JS, et al. Eukaryot Cell. 2011 Jan;10(1):118-29. doi: 10.1128/EC.00246-10. Epub 2010 Nov 5. Eukaryot Cell. 2011. PMID: 21057056 Free PMC article.
These silencing and chromatin changes are not seen upon deletion of HTA2-HTB2, the primary histone locus regulated by Spt10 and Spt21. ...
These silencing and chromatin changes are not seen upon deletion of HTA2-HTB2, the primary histone locus regulated by Spt10 an …
Progression into the first meiotic division is sensitive to histone H2A-H2B dimer concentration in Saccharomyces cerevisiae.
Tsui K, Simon L, Norris D. Tsui K, et al. Genetics. 1997 Mar;145(3):647-59. doi: 10.1093/genetics/145.3.647. Genetics. 1997. PMID: 9055075 Free PMC article.
The yeast Saccharomyces cerevisiae contains two genes for histone H2A and two for histone H2B located in two divergently transcribed gene pairs: HTA1-HTB1 and HTA2-HTB2. Diploid strains lacking HTA1-HTB1 (hta1-htb1 delta/hta1-htb1 delta, HTA2-HTB2/H …
The yeast Saccharomyces cerevisiae contains two genes for histone H2A and two for histone H2B located in two divergently transcribed gene pa …
Histone H2BK123 monoubiquitination is the critical determinant for H3K4 and H3K79 trimethylation by COMPASS and Dot1.
Nakanishi S, Lee JS, Gardner KE, Gardner JM, Takahashi YH, Chandrasekharan MB, Sun ZW, Osley MA, Strahl BD, Jaspersen SL, Shilatifard A. Nakanishi S, et al. J Cell Biol. 2009 Aug 10;186(3):371-7. doi: 10.1083/jcb.200906005. J Cell Biol. 2009. PMID: 19667127 Free PMC article.
Furthermore, we report that Y131, one of the yeast histone H2A/H2B shuffle strains widely used for the last decade in the field of chromatin and transcription biology, carries a wild-type copy of each of the HTA2 and HTB2 genes under the GAL1/10 promoter on chromoso …
Furthermore, we report that Y131, one of the yeast histone H2A/H2B shuffle strains widely used for the last decade in the field of chromatin …
Spt10-dependent transcriptional activation in Saccharomyces cerevisiae requires both the Spt10 acetyltransferase domain and Spt21.
Hess D, Liu B, Roan NR, Sternglanz R, Winston F. Hess D, et al. Mol Cell Biol. 2004 Jan;24(1):135-43. doi: 10.1128/MCB.24.1.135-143.2004. Mol Cell Biol. 2004. PMID: 14673149 Free PMC article.
Our results show that activation by Spt10 is dependent on its acetyltransferase domain. At HTA2-HTB2, the histone locus whose transcription is most strongly dependent on Spt10, Spt10 is physically recruited to the promoter in an Spt21-dependent and a cell cycle-depe …
Our results show that activation by Spt10 is dependent on its acetyltransferase domain. At HTA2-HTB2, the histone locus whose …
11 results